Poliomyelitis Antibodies in Two Differing Socioeconomic Groups within the same City ‡
نویسندگان
چکیده
The study of the epidemiology of poliomyelitis has been complicated by the high ratio of inapparent to clinically recognizable infections and, until recently, by the lack of availability of practical laboratory methods to detect infected persons. A number of normal population groups have been surveyed for virus-neutralizing antibodies, which persist for many years, if not for life, and allow one to observe patterns of accumulated experience with poliomyelitis infections."' 7'9 Recently, tests for complement-fixing (C-F) antibodies have become available. These antibodies are relatively shortlived and thus are an index of relatively recent infection.1'2'8'8 The present paper describes the first application of both neutralization and C-F tests to a survey of poliomyelitis infection in a city within this country, viz., Charleston, West Virginia. For this study, two population groups of differing socioeconomic status were selected. Antibodies against Type 2 poliomyelitis virus were measured in paired serum specimens collected in the spring and summer of 1951, and their age-specific prevalence considered in relation to environment and to the incidence of clinical poliomyelitis.
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عنوان ژورنال:
- The Yale Journal of Biology and Medicine
دوره 27 شماره
صفحات -
تاریخ انتشار 1955